GO:0036503 biological_process ERAD pathway
| PAG Title | GO:0036503 biological_process ERAD pathway |
| PAG ID | TAX023422 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 496 |
| Information Content | Rich |
| Other IDs | GO:0036503 |
| Base PAG ID | TAX023422 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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